By Tao Le, Vikas Bhushan
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Extra resources for First Aid for the USMLE Step 1 2013 (First Aid USMLE)
Tradition on chocolate agar calls for components V (NAD+) and X ( hematin) for development ; can be grown with S. aureus, which supplies issue V. deal with meningitis with ceftriaxone. Rifampin prophylaxis in shut contacts. whilst a ch ild has "Au," mother is going to 5 (V) and clime (X) shop to shop for a few chocolate. Vaccine comprises kind B capsular polysaccharide (polyribosyl ribitol phosphate) conjugated to d iphtheria toxoid or different protein. Given among 2 and 18 months of age. doesn't reason the Au (influenza virus does) . M I C R OB I OLO G Y � M I C R O B I O L O G Y - C LIN I CAL BACTERIO L O G Y SECT I O N I I 1 35 Legionella pneumophila Legi o n n a i res' d isease = serious pneumon ia, fever, GI and CNS indicators. Po ntiac fever = gentle Au-like syndrome. Gram-negative rod. Gram stains poorly-use silver stain. develop on charcoal yeast extract tradition with iron and cysteine. Detected clinically through presence of antigen in urine. Aerosol transm ission from environmental water resource habitat. o person-to-person transmission. therapy: macrol ide or quinolone. examine a French legionnaire (soldier) along with his silver helmet, sitting round a campfire (charcoal) with hello s iron dagger- he's no sissy (cysteine). Labs exhibit hyponatremia. Pseudomonas PSE UDOmonas is linked to wound and burn infections, Pneumonia (especially in cystic fibrosis), Sepsis (black lesions on ski n) , exterior otitis (swim mer's ear) , UTI , Drug use and Diabetic Osteomyelitis, and scorching bath foll iculitis. Mal ignant otitis externa in diabetics. cardio gram-negative rod. Non-lactose fermenting, oxidase optimistic. Produces pyocyanin (blue-green) pigment; has a grape-like scent. Water resource. Produces endotoxin (fever, surprise) and exotoxin A (inactivates E F-2 ) . remedy: am inoglycoside plus prolonged spectrum penicillin (e. g. , piperacillin, ticarcillin). Aeruginosa - cardio. imagine water connection and blue-green pigment. imagine Pseudomonas in burn victi ms. power pneumonia in C F sufferers is linked to biofi l m . aeruginosa E. coli E. coli virulence components : fimbriae- cystitis a n d pyelonephriti s ; ok capsule-pneumonia, neonatal meningiti s ; LPS endotoxin- septic surprise . pressure TOXI N AND M ECHANISM PRESENTATION E IEC M icrobe i nvades intestinal mucosa and reasons necrosis and inflam mation. No pollutants produced. Clin ical manifestations just like Shigella . Invasive ; dysentery. ETEC Labile toxi n /stable toxin. No irritation or invasion . Traveler's diarrhea (watery) . EPEC No toxin produced. Adheres to apical floor, flattens villi, prevents absorption. Diarrhea often i n kids (Ped iatrics) . EH EC O l fifty seven: H 7 is the commonest serotype. Produces Dysentery (toxin by myself factors necrosis and Shiga-l ike toxin and Hemolytic-uremic inflam mation ) . syndrome (triad of anem ia, th rombocytopenia, D o e s n o t ferment sorbitol (d istingu ishes it from and acute renal failure) . different E. coli) . Endothel ium swells and narrows lumen , resulting in mechanical hemolysis and lowered renal blood movement; broken endothelium consumes platelets.